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News

February 27, 2024

Xing Wang and team develop new method of COVID prevention

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May 03, 2023

PhD candidate Jazmin Galvan Achi awarded College of Medicine Dean's Scholar Fellowship

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March, 2023

PhD candidate Jazmin Galvan Achi wins 1st place for ICAR2023 Poster Award

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January 31, 2023

Faculty named Fellows of the American Association for the Advancement of Science

 

August 8, 2022

Developing antivirals for pandemic-level viruses 

 

May 18, 2022

NIH announces antiviral drug development awards

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February 25, 2022

Sunshine Biopharma Expands Anti-Coronavirus Drug Development Program By Signing A Collaboration Agreement With The University Of Arizona

 

January 19, 2022

‘Decoy’ protein works against multiple SARS-CoV-2 variants

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September 23, 2021

Aptamer-nanopore sensor detects only infectious viruses

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September 22, 2021

DNA sensor quickly determines whether viruses are infectious

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March 31, 2021

Novel COVID-19 drug blocks viral replication

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February 8, 2021

New drug target for Ebola, Marburg viruses

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August 11, 2015

Existing class of drugs may halt Ebola, Marburg viruses

 

Aug 10, 2015

Strategy Used for Allergy Medication May Inhibit Ebola

 

August 7, 2015

Familiar drugs may block Ebola virus infection

 

August 12, 2014

UIC researchers seek keys to prevent Ebola infection 

 

October 23, 2013

Food additive may prevent spread of deadly new avian flu

 

January 19, 2011

Small molecules may prevent ebola infection

Publications

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Bibliography Link: https://www.ncbi.nlm.nih.gov/myncbi/1HYmc5Sf3dA5b/bibliography/public/

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2024

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Li Z, Li B, Liu M, Chen Z, Li P, Du R, Su M, Anirudhan V, Achi JG, Tian J, Rong L, Cui Q. Development of a virus-based affinity ultrafiltration method for screening virus-surface-protein-targeted compounds from complex matrixes: Herbal medicines as a case study. Journal of Medical Virology. 2024 March 13; 96(3):e29517. doi: 10.1002/jmv.29517

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Song T, Cooper L, Achi JG, Wang X, Dwivedy A, Rong L, Wang X. Polyvalent Nanobody Structure Designed for Boosting SARS-CoV-2 Inhibition. Journal of the American Chemical Society Article ASAP. 2024 Feb 26; DOI: 10.1021/jacs.3c11760

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Gaisina I, Li P, Du R, Cui Q, Dong M, Zhang C, Manicassamy B, Caffrey M, Moore T, Cooper L, Rong L. An orally active entry inhibitor of influenza A viruses protects mice and synergizes with oseltamivir and baloxavir marboxil. Science Advances. 2024 Feb 23; 10(8). doi: 10.1126/sciadv.adk9004.

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Dong M, Achi JG, Du R, Rong L, Cui Q. Development of SARS-CoV-2 entry antivirals. Cell Insight. 2024 Jan; 3(1). doi: 10.1016/j.cellin.2023.100144.

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Liu M, Li Z, Cui Q, Yan B, Achi JG, Zhao Y, Rong L, Du R. Integrated serum pharmacochemistry and investigation of the anti-influenza A virus pneumonia effect of Qingjin Huatan decoction. J Ethnopharmacol. 2024 Jan 5:117701. doi: 10.1016/j.jep.2024.117701. Epub ahead of print. PMID: 38185258.

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Du R, Achi JG, Cui Q, Rong L. Paving new roads toward the advancement of broad-spectrum antiviral agents. J Med Virol. 2024 Jan;96(1):e29369. doi: 10.1002/jmv.29369. Review. PubMed PMID: 38180269.

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2023

 

Izaguirre G, Phan L, Asif S, Alam S, Meyers C, Rong L. Diversity in Proprotein Convertase Reactivity among Human Papillomavirus Types. Viruses. 2024; 16(1). doi: 10.3390/v16010039.


Ping Li, Han Ju, Yihong Xing, Fabao Zhao, Varada Anirudhan, Ruikun Du, Qinghua Cui, Xinyong Liu, Lijun Rong, and Peng ZhanIdentification of the Imidazo[1,2-a]pyrazine Derivative A4 as a Potential Influenza Virus Nucleoprotein Inhibitor. ACS Pharmacology & Translational Science. Article ASAP. 2023 Nov 17;. DOI: 10.1021/acsptsci.3c00174

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Zhu M, Anirudhan V, Du R, Rong L, Cui Q. Influenza virus cell entry and targeted antiviral development. J Med Virol. 2023 Nov;95(11):e29181. doi: 10.1002/jmv.29181. Review. PubMed PMID: 37930075.

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Liang CY, Huang I, Han J, Sownthirarajan B, Kulhankova K, Murray NB, Taherzadeh M, Archer-Hartmann S, Pepi L, Manivasagam S, Plung J, Sturtz M, Yu Y, Vogel OA, Kandasamy M, Gourronc FA, Klingelhutz AJ, Choudhury B, Rong L, Perez JT, Azadi P, McCray PB Jr, Neelamegham S, Manicassamy B. Avian influenza A viruses exhibit plasticity in sialylglycoconjugate receptor usage in human lung cells. J Virol. 2023 Oct 16;:e0090623. doi: 10.1128/jvi.00906-23. [Epub ahead of print] PubMed PMID: 37843369.

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Dong M, Wang Y, Li P, Chen Z, Anirudhan V, Cui Q, Rong L, Du R. Allopregnanolone targets nucleoprotein as a novel influenza virus inhibitor. Virol Sin. 2023 Sep 21;. doi: 10.1016/j.virs.2023.09.003. [Epub ahead of print] PubMed PMID: 37741571.

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Li Z, Li B, Chen Z, Xu J, El Sabbagh A, Zhao Y, Du R, Rong L, Tian J, Cui Q. Licochalcone A plays dual antiviral roles by inhibiting RSV and protecting against host damage. J Med Virol. 2023 Aug;95(8):e29059. doi: 10.1002/jmv.29059. PubMed PMID: 37635463.

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Li P, Ju H, Zhang Y, Achi JG, Kang D, Zou J, Du R, Cui Q, Liu X, Rong L, Zhan P. Discovery of ligustrazine and chalcone derivatives as novel viral nucleoprotein nuclear export inhibitors against influenza viruses. J Med Virol. 2023 Jul;95(7):e28968. doi: 10.1002/jmv.28968. PubMed PMID: 37489704.

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Liu M, Zhao F, Xu J, Zhu X, Zhao Y, Wen R, Anirudhan V, Rong L, Tian J, Cui Q. Qingjin Huatan decoction protects mice against influenza a virus pneumonia via the chemokine signaling pathways. Journal of Ethnopharmacology. 2023/06; :116745.

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Lin X, Zhu M, Zhao X, Si L, Dong M, Anirudhan V, Cui Q, Rong L, Du R. Optimization and applications of an in vivo bioluminescence imaging model of influenza a virus infections. Virologica Sinica. 2023/05.

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Chen Z, Du R, Cooper L, Achi JG, Dong M, Ran Y, Zhang J, Zhan P, Rong L, Cui Q. Sulforaphane is a reversible covalent inhibitor of 3-chymotrypsin-like protease of SARS-CoV-2. J Med Virol. 2023 Feb 24;. doi: 10.1002/jmv.28609. [Epub ahead of print] PubMed PMID: 36840402.

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2022

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Zhang C, Zhang G, Zhang Y, Lin X, Zhao X, Cui Q, Rong L, Du R. Development of an HiBiT-tagged reporter H3N2 influenza A virus and its utility as an antiviral screening platform. J Med Virol. 2022 Nov 24;. doi: 10.1002/jmv.28345. [Epub ahead of print] PubMed PMID: 36424458.

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Du R, Cui Q, Chen Z, Zhao X, Lin X, Rong L. Revisiting influenza A virus life cycle from a perspective of genome balance. Virol Sin. 2022 Oct 26;. doi: 10.1016/j.virs.2022.10.005. [Epub ahead of print] Review. PubMed PMID: 36309307.

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Alqarni S, Cooper L, Galvan Achi J, Bott R, Sali VK, Brown A, Santarsiero BD, Krunic A, Manicassamy B, Peet NP, Zhang P, Thatcher GRJ, Gaisina IN, Rong L, Moore TW. Synthesis, Optimization, and Structure-Activity Relationships of Imidazo[1,2-a]pyrimidines as Inhibitors of Group 2 Influenza A Viruses. J Med Chem. 2022 Oct 27;65(20):14104-14120. doi: 10.1021/acs.jmedchem.2c01329. Epub 2022 Oct 19. PubMed PMID: 36260129.

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Zhang L, Narayanan KK, Cooper L, Chan KK, Devlin CA, Aguhob A, Shirley K, Rong L, Rehman J, Malik AB, Procko E. An engineered ACE2 decoy receptor can be administered by inhalation and potently targets the BA.1 and BA.2 omicron variants of SARS-CoV-2. EMBO Mol Med. 2022 Mar 28;. doi: 10.1101/2022.03.28.486075. PubMed PMID: 35378764; PubMed Central PMCID: PMC8978935.

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Zhao X, Lin X, Li P, Chen Z, Zhang C, Manicassamy B, Rong L, Cui Q, Du R. Expanding the tolerance of segmented Influenza A Virus genome using a balance compensation strategy. PLoS Pathog. 2022 Aug;18(8):e1010756. doi: 10.1371/journal.ppat.1010756. eCollection 2022 Aug. PubMed PMID: 35926068; PubMed Central PMCID: PMC9380948.

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Zhao Y, Tsang N, Xu X, Zhao C, Ku C, Li W, Zhu Y, Liu K, Rong L, Zhang H. Axial Chirality and Antiviral Activity Evaluation of Arylnaphthalene Lignan Glycosides from Justicia procumbens. Asian Journal of Organic Chemistry. 2022 June. doi: 10.1002/ajoc.202200267.

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Li WF, Liang ZM, Zhao CL, Tsang NY, Li JX, Liu YH, He K, Pan LT, Rong L, Zou J, Zhang HJ. 3,4-Seco-Isopimarane Diterpenes from the Twigs and Leaves of Isodon Flavidus. Molecules. 2022 May 12;27(10). doi: 10.3390/molecules27103098. PubMed PMID: 35630575.

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Qing E, Li P, Cooper L, Schulz S, Jäck HM, Rong L, Perlman S, Gallagher T. Inter-domain communication in SARS-CoV-2 spike proteins controls protease-triggered cell entry. Cell Rep. 2022 May 3;39(5):110786. doi: 10.1016/j.celrep.2022.110786. Epub 2022 Apr 19. PubMed PMID: 35477024; PubMed Central PMCID: PMC9015963.

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Du R, Cui Q, Caffrey M, Rong L. Ebola Virus Entry Inhibitors. Adv Exp Med Biol. 2022;1366:155-170. doi: 10.1007/978-981-16-8702-0_10. PubMed PMID: 35412140.

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Cooper L, Galvan Achi J, Rong L. Comparative analyses of small molecule and antibody inhibition on glycoprotein-mediated entry of MÄ›nglà virus with other filoviruses. J Med Virol. 2022 Jul;94(7):3263-3269. doi: 10.1002/jmv.27739. Epub 2022 Apr 5. PubMed PMID: 35332563; PubMed Central PMCID: PMC9161972.

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Tsang NY, Li WF, Varhegyi E, Rong L, Zhang HJ. Ebola Entry Inhibitors Discovered from Maesa perlarius. Int J Mol Sci. 2022 Feb 27;23(5). doi: 10.3390/ijms23052620. PubMed PMID: 35269770; PubMed Central PMCID: PMC8910447.

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Wang Z, Kim J, Zhang P, Galvan Achi JM, Jiang Y, Rong L. Current therapy and development of therapeutic agents for lung cancer. Cell Insight. 2022 February; 1(2). doi: https://doi.org/10.1016/j.cellin.2022.100015.

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Iwanaga N, Cooper L, Rong L, Maness NJ, Beddingfield B, Qin Z, Crabtree J, Tripp RA, Yang H, Blair R, Jangra S, García-Sastre A, Schotsaert M, Chandra S, Robinson JE, Srivastava A, Rabito F, Qin X, Kolls JK. ACE2-IgG1 fusions with improved in vitro and in vivo activity against SARS-CoV-2. iScience. 2022 Jan 21;25(1):103670. doi: 10.1016/j.isci.2021.103670. Epub 2021 Dec 20. PubMed PMID: 34957381; PubMed Central PMCID: PMC8686446.

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Zhang L, Dutta S, Xiong S, Chan M, Chan KK, Fan TM, Bailey KL, Lindeblad M, Cooper LM, Rong L, Gugliuzza AF, Shukla D, Procko E, Rehman J, Malik AB. Engineered ACE2 decoy mitigates lung injury and death induced by SARS-CoV-2 variants. Nat Chem Biol. 2022 Mar;18(3):342-351. doi: 10.1038/s41589-021-00965-6. Epub 2022 Jan 19. PubMed PMID: 35046611; PubMed Central PMCID: PMC8885411.

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2021

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Li N, Wang X, Tibbs J, Che C, Peinetti AS, Zhao B, Liu L, Barya P, Cooper L, Rong L, Wang X, Lu Y, Cunningham BT. Label-Free Digital Detection of Intact Virions by Enhanced Scattering Microscopy. J Am Chem Soc. 2022 Feb 2;144(4):1498-1502. doi: 10.1021/jacs.1c09579. Epub 2021 Dec 20. PubMed PMID: 34928591.

 

Malicoat J, Manivasagam S, Zuñiga S, Sola I, McCabe D, Rong L, Perlman S, Enjuanes L, Manicassamy B. Development of a Single-Cycle Infectious SARS-CoV-2 Virus Replicon Particle System for Use in Biosafety Level 2 Laboratories. J Virol. 2022 Feb 9;96(3):e0183721. doi: 10.1128/JVI.01837-21. Epub 2021 Dec 1. PubMed PMID: 34851142; PubMed Central PMCID: PMC8826801.

 

Shen Z, Ratia K, Cooper L, Kong D, Lee H, Kwon Y, Li Y, Alqarni S, Huang F, Dubrovskyi O, Rong L, Thatcher GRJ, Xiong R. Design of SARS-CoV-2 PLpro Inhibitors for COVID-19 Antiviral Therapy Leveraging Binding Cooperativity. J Med Chem. 2022 Feb 24;65(4):2940-2955. doi: 10.1021/acs.jmedchem.1c01307. Epub 2021 Oct 19. PubMed PMID: 34665619; PubMed Central PMCID: PMC8547495.

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Peinetti AS, Lake RJ, Cong W, Cooper L, Wu Y, Ma Y, Pawel GT, Toimil-Molares ME, Trautmann C, Rong L, Mariñas B, Azzaroni O, Lu Y. Direct detection of human adenovirus or SARS-CoV-2 with ability to inform infectivity using DNA aptamer-nanopore sensors. Sci Adv. 2021 Sep 24;7(39):eabh2848. doi: 10.1126/sciadv.abh2848. Epub 2021 Sep 22. PubMed PMID: 34550739; PubMed Central PMCID: PMC8457657.

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Amaya M, Cheng H, Borisevich V, Navaratnarajah CK, Cattaneo R, Cooper L, Moore TW, Gaisina IN, Geisbert TW, Rong L, Broder CC. A recombinant Cedar virus based high-throughput screening assay for henipavirus antiviral discovery. Antiviral Res. 2021 Sep;193:105084. doi: 10.1016/j.antiviral.2021.105084. Epub 2021 May 30. PubMed PMID: 34077807.

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Yang J, Perez EA, Hou C, Zhang P, Van Scoyk M, Winn RA, Rong L, Liu J. Identification of the SARS-CoV-2 Entry Receptor ACE2 as a Direct Target for Transcriptional Repression by Miz1. Front Immunol. 2021;12:648815. doi: 10.3389/fimmu.2021.648815. eCollection 2021. PubMed PMID: 34305888; PubMed Central PMCID: PMC8292894.

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Chen Z, Cui Q, Caffrey M, Rong L, Du R. Small Molecule Inhibitors of Influenza Virus Entry. Pharmaceuticals (Basel). 2021 Jun 18;14(6). doi: 10.3390/ph14060587. Review. PubMed PMID: 34207368; PubMed Central PMCID: PMC8234048.

 

Wang Z, Peet NP, Zhang P, Jiang Y, Rong L. Current Development of Glioblastoma Therapeutic Agents. Mol Cancer Ther. 2021 Sep;20(9):1521-1532. doi: 10.1158/1535-7163.MCT-21-0159. Epub 2021 Jun 25. Review. PubMed PMID: 34172531.

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Sarute N, Cheng H, Yan Z, Salas-Briceno K, Richner J, Rong L, Ross SR. Signal-regulatory protein alpha is an anti-viral entry factor targeting viruses using endocytic pathways. PLoS Pathog. 2021 Jun;17(6):e1009662. doi: 10.1371/journal.ppat.1009662. eCollection 2021 Jun. PubMed PMID: 34097709; PubMed Central PMCID: PMC8211255.

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Chen Z, Du R, Galvan Achi JM, Rong L, Cui Q. SARS-CoV-2 cell entry and targeted antiviral development. Acta Pharm Sin B. 2021 Dec;11(12):3879-3888. doi: 10.1016/j.apsb.2021.05.007. Epub 2021 May 13. Review. PubMed PMID: 34002130; PubMed Central PMCID: PMC8117542.

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Li P, Du R, Chen Z, Wang Y, Zhan P, Liu X, Kang D, Chen Z, Zhao X, Wang L, Rong L, Cui Q. Punicalagin is a neuraminidase inhibitor of influenza viruses. J Med Virol. 2021 Jun;93(6):3465-3472. doi: 10.1002/jmv.26449. Epub 2020 Sep 29. PubMed PMID: 32827314.

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Wan T, Liu X, Su Y, Zou J, Wu X, Jiang C, Cao C, Yao M, Zhou Y, Rong L, Li B, Wen L, Feng Q. Biological differentiation of traditional Chinese medicine from excessive to deficient syndromes in AIDS: Comparative microRNA microarray profiling and syndrome-specific biomarker identification. J Med Virol. 2021 Jun;93(6):3634-3646. doi: 10.1002/jmv.26704. Epub 2020 Dec 17. PubMed PMID: 33289096.

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Anirudhan V, Lee H, Cheng H, Cooper L, Rong L. Targeting SARS-CoV-2 viral proteases as a therapeutic strategy to treat COVID-19. J Med Virol. 2021 May;93(5):2722-2734. doi: 10.1002/jmv.26814. Epub 2021 Feb 9. Review. PubMed PMID: 33475167; PubMed Central PMCID: PMC8014870.

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Du R, Cooper L, Chen Z, Lee H, Rong L, Cui Q. Discovery of chebulagic acid and punicalagin as novel allosteric inhibitors of SARS-CoV-2 3CLpro. Antiviral Res. 2021 Jun;190:105075. doi: 10.1016/j.antiviral.2021.105075. Epub 2021 Apr 17. PubMed PMID: 33872675; PubMed Central PMCID: PMC8052511.

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Zhao Y, Ku CF, Xu XY, Tsang NY, Zhu Y, Zhao CL, Liu KL, Li CC, Rong L, Zhang HJ. Stable Axially Chiral Isomers of Arylnaphthalene Lignan Glycosides with Antiviral Potential Discovered from Justicia procumbens. J Org Chem. 2021 Apr 16;86(8):5568-5583. doi: 10.1021/acs.joc.1c00068. Epub 2021 Apr 5. PubMed PMID: 33818100.

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Chen Z, Cui Q, Cooper L, Zhang P, Lee H, Chen Z, Wang Y, Liu X, Rong L, Du R. Ginkgolic acid and anacardic acid are specific covalent inhibitors of SARS-CoV-2 cysteine proteases. Cell Biosci. 2021 Feb 28;11(1):45. doi: 10.1186/s13578-021-00564-x. PubMed PMID: 33640032; PubMed Central PMCID: PMC7914117.

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Schafer A, Xiong R, Cooper L, Nowar R, Lee H, Li Y, Ramirez BE, Peet NP, Caffrey M, Thatcher GRJ, Saphire EO, Cheng H, Rong L. Evidence for distinct mechanisms of small molecule inhibitors of filovirus entry. PLoS Pathog. 2021 Feb;17(2):e1009312.  doi: 10.1371/journal.ppat.1009312. eCollection 2021 Feb. PubMed PMID: 33539432; PubMed Central PMCID: PMC7888603.

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Du R, Cui Q, Rong L. Flu Universal Vaccines: New Tricks on an Old Virus. Virol Sin. 2021 Feb;36(1):13-24. doi: 10.1007/s12250-020-00283-6. Epub 2020 Sep 1. Review. PubMed PMID: 32870450; PubMed Central PMCID: PMC7459973.

 

Du R, Cheng H, Cui Q, Peet NP, Gaisina IN, Rong L. Identification of a novel inhibitor targeting influenza A virus group 2 hemagglutinins. Antiviral Res. 2021 Feb;186:105013. doi: 10.1016/j.antiviral.2021.105013. Epub 2021 Jan 8. PubMed PMID: 33428962.

 

Wang Y, Anirudhan V, Du R, Cui Q, Rong L. RNA-dependent RNA polymerase of SARS-CoV-2 as a therapeutic target. J Med Virol. 2021 Jan;93(1):300-310. doi: 10.1002/jmv.26264. Epub 2020 Jul 19. Review. PubMed PMID: 32633831.

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2020

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Gao Y, Cheng H, Khan S, Xiao G, Rong L, Bai C. Development of coumarine derivatives as potent anti-filovirus entry inhibitors targeting viral glycoprotein. Eur J Med Chem. 2020 Oct 15;204:112595. doi: 10.1016/j.ejmech.2020.112595. Epub 2020 Jul 12. PubMed PMID: 32707357; PubMed Central PMCID: PMC7529935.

 

Kang Q, Wang Y, Cui Q, Gong L, Yang Y, Jiang H, Rong L, Rong R, Du R. Screening for Anti-Influenza Actives of Prefractionated Traditional Chinese Medicines. Evid Based Complement Alternat Med. 2020;2020:4979850. doi: 10.1155/2020/4979850. eCollection 2020. PubMed PMID: 33123207; PubMed Central PMCID: PMC7584957.

 

Cooper L, Schafer A, Li Y, Cheng H, Medegan Fagla B, Shen Z, Nowar R, Dye K, Anantpadma M, Davey RA, Thatcher GRJ, Rong L, Xiong R. Screening and Reverse-Engineering of Estrogen Receptor Ligands as Potent Pan-Filovirus Inhibitors. J Med Chem. 2020 Oct 8;63(19):11085-11099. doi: 10.1021/acs.jmedchem.0c01001. Epub 2020 Sep 22. PubMed PMID: 32886512; PubMed Central PMCID: PMC7904233.

 

Ewenighi-Amankwah CO, Onyenekwe CC, Udemba O, Muogbo P, Rong L. A Mother-to-Child Transmission Study in Nigeria: The Impact of Maternal HIV Infection and HAART on Plasma Immunoglobulins, Cytokine Profiles and Infant Outcome. Virol Sin. 2020 Aug;35(4):468-477. doi: 10.1007/s12250-020-00202-9. Epub 2020 Mar 10. PubMed PMID: 32157604; PubMed Central PMCID: PMC7462942.

 

Antanasijevic A, Durst MA, Cheng H, Gaisina IN, Perez JT, Manicassamy B, Rong L, Lavie A, Caffrey M. Structure of avian influenza hemagglutinin in complex with a small molecule entry inhibitor. Life Sci Alliance. 2020 Aug;3(8). doi: 10.26508/lsa.202000724. Print 2020 Aug. PubMed PMID: 32611549; PubMed Central PMCID: PMC7335401.

 

Gaisina IN, Peet NP, Wong L, Schafer AM, Cheng H, Anantpadma M, Davey RA, Thatcher GRJ, Rong L. Discovery and Structural Optimization of 4-(Aminomethyl)benzamides as Potent Entry Inhibitors of Ebola and Marburg Virus Infections. J Med Chem. 2020 Jul 9;63(13):7211-7225. doi: 10.1021/acs.jmedchem.0c00463. Epub 2020 Jun 17. PubMed PMID: 32490678; PubMed Central PMCID: PMC7671190.

 

Liu X, Wu Y, Rong L. Conditionally Reprogrammed Human Normal Airway Epithelial Cells at ALI: A Physiological Model for Emerging Viruses. Virol Sin. 2020 Jun;35(3):280-289. doi: 10.1007/s12250-020-00244-z. Epub 2020 Jun 17. Review. PubMed PMID: 32557270; PubMed Central PMCID: PMC7298165.

 

Hussein AFA, Cheng H, Tundup S, Antanasijevic A, Varhegyi E, Perez J, AbdulRahman EM, Elenany MG, Helal S, Caffrey M, Peet N, Manicassamy B, Rong L. Identification of entry inhibitors with 4-aminopiperidine scaffold targeting group 1 influenza A virus. Antiviral Res. 2020 May;177:104782. doi: 10.1016/j.antiviral.2020.104782. Epub 2020 Mar 25. PubMed PMID: 32222293; PubMed Central PMCID: PMC7243365.

 

Gaisina IN, Peet NP, Cheng H, Li P, Du R, Cui Q, Furlong K, Manicassamy B, Caffrey M, Thatcher GRJ, Rong L. Optimization of 4-Aminopiperidines as Inhibitors of Influenza A Viral Entry That Are Synergistic with Oseltamivir. J Med Chem. 2020 Mar 26;63(6):3120-3130. doi: 10.1021/acs.jmedchem.9b01900. Epub 2020 Mar 2. PubMed PMID: 32069052.

 

Li P, Du R, Wang Y, Hou X, Wang L, Zhao X, Zhan P, Liu X, Rong L, Cui Q. Identification of Chebulinic Acid and Chebulagic Acid as Novel Influenza Viral Neuraminidase Inhibitors. Front Microbiol. 2020;11:182. doi: 10.3389/fmicb.2020.00182. eCollection 2020. PubMed PMID: 32256457; PubMed Central PMCID: PMC7093024.

 

Wen L, Jiang C, Wan TJ, Wang D, Yan D, Li GY, Su Y, Liu XY, Rong LJ, Ye H, Li BX, Feng QS. Biological Differentiation of Dampness-Heat Syndromes in Chronic Hepatitis B: From Comparative MicroRNA Microarray Profiling to Biomarker Identification. Evid Based Complement Alternat Med. 2020;2020:7234893. doi: 10.1155/2020/7234893. eCollection 2020. PubMed PMID: 32051688; PubMed Central PMCID: PMC6995329.

 

Cui Q, Du R, Liu M, Rong L. Lignans and Their Derivatives from Plants as Antivirals. Molecules. 2020 Jan 1;25(1). doi: 10.3390/molecules25010183. Review. PubMed PMID: 31906391; PubMed Central PMCID: PMC6982783.

 

 

 

2019

 

Xu XY, Wang DY, Ku CF, Zhao Y, Cheng H, Liu KL, Rong LJ, Zhang HJ. Anti-HIV lignans from Justicia procumbens. Chin J Nat Med. 2019 Dec;17(12):945-952. doi: 10.1016/S1875-5364(19)30117-7. PubMed PMID: 31882050.

 

Martinez-Lopez A, Persaud M, Chavez MP, Zhang H, Rong L, Liu S, Wang TT, Sarafianos SG, Diaz-Griffero F. Glycosylated diphyllin as a broad-spectrum antiviral agent against Zika virus. EBioMedicine. 2019 Sep;47:269-283. doi: 10.1016/j.ebiom.2019.08.060. Epub 2019 Sep 6. PubMed PMID: 31501074; PubMed Central PMCID: PMC6796538.

 

Zhao X, Wang Y, Cui Q, Li P, Wang L, Chen Z, Rong L, Du R. A Parallel Phenotypic Versus Target-Based Screening Strategy for RNA-Dependent RNA Polymerase Inhibitors of the Influenza A Virus. Viruses. 2019 Sep 5;11(9). doi: 10.3390/v11090826. PubMed PMID: 31491939; PubMed Central PMCID: PMC6783926.

 

Wang L, Cui Q, Zhao X, Li P, Wang Y, Rong L, Du R. Generation of a Reassortant Influenza A Subtype H3N2 Virus Expressing Gaussia Luciferase. Viruses. 2019 Jul 20;11(7). doi: 10.3390/v11070665. PubMed PMID: 31330768; PubMed Central PMCID: PMC6669691.

 

Du R, Cui Q, Rong L. Competitive Cooperation of Hemagglutinin and Neuraminidase during Influenza A Virus Entry. Viruses. 2019 May 20;11(5). doi: 10.3390/v11050458. Review. PubMed PMID: 31137516; PubMed Central PMCID: PMC6563287.

 

Pan JH, Zhou H, Cooper L, Huang JL, Zhu SB, Zhao XX, Ding H, Pan YL, Rong L. LAYN Is a Prognostic Biomarker and Correlated With Immune Infiltrates in Gastric and Colon Cancers. Front Immunol. 2019;10:6. doi: 10.3389/fimmu.2019.00006. eCollection 2019. PubMed PMID: 30761122; PubMed Central PMCID: PMC6362421.

 

 

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